The ODI methodology was first documented at scale in the Cordis case (Ulwick, HBR 2002): a maker of angioplasty balloons grew from <1% market share to 10% in the US, 18% in Japan, 20% in Europe and 30% in Canada. Cordis launched 12 new catheters and went on to create the modern coronary stent — one of the most successful medical devices in history.
What Cordis did wasn’t magic: they interviewed cardiologists, nurses and hospital administrators about every step of the angioplasty procedure — and translated the answers into ~75 outcomes after 30 interviews. The outcomes with high importance and low satisfaction (“minimize restenosis”) became development priorities. The result: a stent that reduced restenosis by 20% and generated ~$1B in first-year revenue.